The waste generated from the industries cause environmental problems. Hence the reuse of this waste material can be emphasized. Marble Dust Powder (MDP) is a developing composite material that will allow the concrète industry to optimise materiel use, generate economic benefits and build structures that will strong, durable and sensitive to environnement. MDP is by-product obtained during the quarrying process from the parent marble rock; which contains high calcium oxide content of more than 50%. The potential use of MDP can be an ideal choice for substituting in a cementitious binder as the reactivity efficiency increases due to the presence of lime. In this research work, the waste MDP passing through 90 microns, has used for investigating of hardened concrete properties. Furthermore, the effect of different percentage replacement of MDP on the compressive strength, splitting tensile strength (Indirect tensile strength) & flexural strength has been observed. In this experimental study, the effect of MDP in concrete on strength is presented. Five concrete mixtures containing 0%, 5%, 10%, and 20% MDP as cement replacement by weight basis has been prepared. Water/cement ratio (0.43) was kept constant, in all the concrete mixes. Compressive strength, split tensile strength & flexural strength of the concrete mixtures has been obtained at 7 and 28 days. The results of the laboratory work showed that replacement of cement with MDP increase, up to 10% for compressive strength, & up to 15% for split tensile strength & flexural strength of concrete.