Introduction: Amitraz is a formamidine pesticide that is used to treat generalised demodicosis in dogs as well as to manage ticks and mites on cattle and sheep. The stimulatory actions of the a2 agonist in amitraz cause its neurotoxic and preconvulsant effects. Aim: To study the clinical features, complications, management and outcome of the patients with acute amitraz intoxication. Material and Methods: Our study is a prospective cross sectional study done on 10 cases presented in emergency medicine department of GMC Miraj. Result: Patients had CNS involvement, miosis/mydriasis, hypotension, bradycardia/tachycardia and nonspecific complaints like pain abdomen, vomiting etc. Gastric lavage was given to every case of amitraz poisoning. Conclusion: In patients who presented with history of pesticide consumption with features of bradycardia, drowsiness and features similar to organophosphorous poison physician should think of amitraz poisoning that will help to initiate rapid treatment for this rare, potentially life threatening intoxication.