An inversion method has been developed in order to quantify the emission fluxes of certain aerosol pollution sources across a wide region in the Northern hemisphere, mainly in Europe and Western Asia. The data employed are the aerosol contribution factors deducted by Positive Matrix Factorization (PMF) on a PM2.5 chemical composition dataset from 16 European and Asian cities for the period 2014 to 2016. The spatial resolution of the method corresponds to the geographic grid cell size of the Lagrangian particle dispersion model 5 (FLEXPART 10.4 , 1 x 1 degree) which was utilized for the air mass backward simulations. The area covered is also related to the location of the 16 cities under study.