Dynamics of changes in biogenic amines and hormones in baby rats whose mothers affected by emotional stress reactions during pregnancy has been presented in this article. For this purpose, the research on rat babies carried out for 5 months, concentrations of dopamine (DA), noradrenaline (NA), serotonin, 5-OT and 5-oxyindolacetic acid (5-OIAA) in blood and hypothalamus, and activity of hormones in blood were studied during these months. The results showed that DA and NA amounts in blood and hypothalamus of rat babies whose mothers were affected by stress reactions during pregnancy were higher compared with normal babies during the entire research. However, activity of 5-OT and 5-OIAA decreased in both environments. Accordingly, hormonal indicators changed sharply. Adaptive and reproductive functions were violated and developmental rate was relatively weak in these babies.