In this book chapter, the authors argue that the United States (US) and Russia never lost interest in Afghanistan. It examines the complex relationship between the two major global powers and their involvement in Afghanistan. The chapter explores whether the US and Russia have been fighting against or supporting the Taliban and their impact on the country's politics and security. Drawing on extensive research and analysis of relevant literature, this chapter sheds light on the geopolitical dynamics that have shaped the US and Russia's policies towards Afghanistan and how they influenced the country's future. Overall, this book chapter provides a comprehensive and insightful perspective on the role of the US and Russia in Post-War Afghanistan.