ROLE OF ANTIBIOTIC IMPREGNATED CEMENT COATED INTRAMEDULLARY NAILING IN ORTHOPAEDICS

descriptionPublicationkeyboard_double_arrow_right Article 31 Mar 2023Publisher:International Journal Of Advanced ResearchJournal:International Journal of Advanced Research, volume 11, pages 1,421-1,428 (eissn: 2320-5407,

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Authors: Pradeep Choudhari ,; Charchit Baurasi ,; Deepesh Mehta; Patidar, Manish;

doi: 10.21474/ijar01/16585 , 10.5281/zenodo.7899403 , 10.5281/zenodo.7899402

ROLE OF ANTIBIOTIC IMPREGNATED CEMENT COATED INTRAMEDULLARY NAILING IN ORTHOPAEDICS

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Abstract

Introduction:Traditionally,thetreatmentstrategyofinfectednon-unionconsistedofsurgicaldebridementandthenasecondprocedureforstability.Theuseofanantibioticcementednailingforinfectednon-unionoftibiaandfemurfracturesavoidstheneedofmorethan1procedureasthenailprovidesstabilityandallowshigherconcentrationofantibioticatthelocalsitethanisachievablewithsystemicantibioticsandisassociatedwithfewersideeffect. MaterialandMethods:Thisisaprospectivestudyof12patientswithdiaphysealfractureoftibiaorfemurwithsignsofinfectionwhoweretreatedusingantibioticcementednailing.Patientswerefollowedupmonthlyfor3months.Infectioncontrolwasevaluatedintermsofclinical,haematologicalandmicrobiologicalparameters. Results:Atthetimeofpresentation11outof12patientshadpusdischarge,whilelocalriseoftemperaturewasthereinallpatients.MostcommonorganismthatwasisolatedincultureswasStaphylococcusaureus.ESRandCRPwaselevatedin9patients.At3monthsfollowupvisit,9outof12patientsresolvedallsignsofinfectionwhile1hadpersistentpositiveculturereports.ESRandCRPwasraisedin3and2patientsrespectively. Conclusion:Antibioticcementednailingdeliversahighconcentrationofantibioticsatthelocalsitewithoutcausinganysystemictoxicityalongwithprovidingstabilityatthefracturesite,therebyconvertingatwo-stageprocedureintoasinglestageprocedurewhichalsoavoidscomplicationsofexternalfixatorhavingbetterpatientcompliance.

Keywords

Antibiotic Cement Nailing Infection Non-Union

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