This archive contains all the code and data to reproduce the results of the associated manuscript: Piovani et al, "Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories". We provide filtered scRNA-seq matrices, protein fasta files for each specie used to run SAMap and GenERA as well as the R-code used to generate the datasets and the jupyter notebook to generate SAMap results. In addition we provide the final Seurat objects and all analysis results which can be consulted without re-running the code.