The interviews were part of the Marie Skłodowska-Curie research project “Digital Humanities Laboratory: Studying the Entanglement of Infrastructure and Technology in Knowledge Production”. The project received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 891155. The goal of the project was to investigate the mechanism of knowledge production in digital humanities and the influence of infrastructure on social and research practices in a laboratory. It aimed to contribute to understanding these complex processes and the development and improvement of digital humanities infrastructure. A set of interviews were conducted with members of King’s Digital Lab, management staff and researchers involved in the lab work. Discussions revolved around the institutional, research, and socio-technical infrastructure of King’s College London and King’s Digital Lab; the social practices of digital projects; the project lifecycle; the use of digital tools in everyday research practices; and the conditions and challenges of conducting research with regards to the lab management, organisation, location, policies, access to resources, and facilities. These files are the transcripts of the interviews that took place in 2021. Research website: https://dhinfra-org.github.io/