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Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences

Authors: Marzieh Eslami Rasekh; Yozen Hernandez; Samantha D. Drinan; Juan Fuxman Bass; Gary Benson;

Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences

Abstract

This repository consists of minisatellite VNTR genotypes for 2,800 samples (2,770 individuals). The raw VCF files were produced using VNTRseek on xxx data sources: 30 high coverage WGS datasets from the 1000 Genomes Project phase 3, 2,504 unrelated genomes from New York Genome Center (NYGC), 253 genomes from Simons Diversity Genome Project (SGDP), two tumor-normal breast cancer samples from Illumina Basespace, haploid genomes CHM1 and CHM13, and seven genomes from the Personal Genome Project from the Genome In A Bottle Consortium (GIAB). Raw VCF files are provided for each data source separately. The raw VCF files were preprocessed (preprocess.sh) to extract genotypes and provided in VNTRseek_preprocessed_data.tar.gz (uncompressed size 10G). The R Markdown code to analyze the preprocessed data and produce figures and tables is also provided (tables_and_figures.Rmd). For more information see the ReadMe file. This work was supported in part by NSF grants IIS-1423022 and DBI-1559829.

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Keywords

minisatellites, genotyping, population specific ministallites, VNTRseek, variable number tandem repeat (VNTR)

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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