EFSA developed a hazard assessment protocol upfront to the re-evaluation of Bisphenol A to ensure an efficient and transparent assessment, in line with the principles highlighted in the EFSA project PROmoting METHods for Evidence Use in scientific assessments. After undergoing a public consultation, the protocol was revised according to the comments received and published in its draft version in 2017 (10.5281/zenodo.1116881). Prior to being applied, and still during its implementation in the BPA assessment, the protocol was tested and slightly revised. This is the final version of the protocol used for the BPA re-evaluation, annexed (Annex A) to the opinion on BPA risk assessment of the EFSA CEP Panel published in April 2023 (https://doi.org/10.2903/j.efsa.2023.6857). The protocol states in detail the methods and/or the criteria that were used in the BPA re-evaluation for data collection, study inclusion, evidence appraisal and integration.