Introduction: This clinical study presents the short-term results of the Pilon fracture treated with open reduction and internal fixation through an anterolateral approach and further re-analyse the different complication rates and outcome percentages during surgical treatment through an anterolateral approach. Materials And Methods: The presentstudy is a prospective descriptive study involving 22 patients with Pilon fracture treated by ORIF through an anterolateral approach at the Department of Orthopaedics, Narayana Medical College and hospital, Nellore, Andhra Pradesh from June 2021 to May 2022. Results: In our study, among 22 cases, the majority of patients were male (77%). The mean age group of our patients has been 40 -60 years. Right-sided injury and left-sided injury are almost equal. Functional outcome was measured using Mazur criteria. According to these, we found that 12 patients (54.54%) had excellent functional outcome, 8 patients (36.36%) had good functional outcome and 2 patients had fair functional outcome following ORIF with anterolateral plate for tibial pilon fractures and are comparable with other studies in the literature review. Discussion: In our study functional outcome was measured using Mazur ankle score. According to these we found 12 patients (54.54%) had excellent functional outcome and 8 patients (36.36%) had good functional outcome and 2 patients (9.1%) had fair functional outcome following open reduction and internal fixation with anterolateral for tibial pilon fracture.