Introduction:Identifying the variations in cerebral dural venous sinus anatomy on magnetic resonance (MR) venography is important for the adequate diagnosis of cerebral venous sinus thrombosis (CVST). There is limited documentation available on gender differences in cerebral dural venous sinus anatomical variants. Aims and Objectives:This study aimed to investigate gender-related variations as well as the typical variance of the cerebral venous system anatomy in asymptomatic individuals as shown by MR venography (3D). Material and Methods:This Hospital-based retrospective study was carried out over 24 months from December 2020 to November 2022 at the Department of Radiodiagnosis, Narayana medical college, Nellore. The study was done on 100 patients. All patients underwent 3D MR Venography on 3.0 Tesla (GE DISCOVERY 750W) MRI machine. Results: 1. Headache was the most prevalent clinical symptom for an MR venography (81%). 2. The most frequent anatomical variant was hypoplastic left transverse sinus (27%). 3. Males had a greater likelihood than females to have a hypoplastic left transverse sinus (12 versus 11). 4. Hypoplastic anterior one-third SSS was the most prevalent anatomical variant of the superior sagittal sinus (SSS). Conclusion:In the current research, the most frequent structural variant was found to be hypoplastic left transverse sinus, which was more prevalent in males than females. Other dural venous sinus structural differences did not show a significant difference between genders.