The main aim of this deliverable is to define GenoMed4All’s hybrid federated learning model specification expressed in terms of platform requirements, which have been acquired by analyzing in details the project’s objectives as well as by decomposing the stakeholders’ needs through the different use cases’ definition. It includes a description of the requirements elicitation methodology together with the set of technical requirements regarding the federated learning approach of the project’s platform. Moreover, it includes an extensive analysis of the most important federated learning framework solutions already available, and it finally defines the evaluation criteria that have helped in the selection of the most appropriate one for the project’s purposes and needs.