In the treatment of postpartum acute purulent catarrhal endometritis in cows, intrauterine administration of 80 ml of the emulsion and intramuscular administration of PENSRIB-400 in a certain norm and amount improve blood and lymph circulation in the pathological focus, reduce inflammation and enhance regeneration processes. The average duration of treatment is 8 days, of which 9 days in animals with purulent catarrhal endometritis and 11 days in animals with purulent catarrhal endometritis of bacterial and fungal etiology.