This article presents a scientific conclusion about the advancement of the cooperation of the Republic of Uzbekistan with the United Nations to a new level and development prospects. On March 2, 2018, it was 26 years since the Republic of Uzbekistan became a member of the United Nations. From this date, Uzbekistan is a full-blooded member of the world community. A representative office of the UN was opened in our capital, Tashkent, and a representative office of Uzbekistan was opened at the UN headquarters in New York. Since then, the flag of our republic has flown in front of the UN headquarters, like the flags of other members of the organization. In this regard, the views of the states are highlighted, conclusions are determined based on the interests of the regions and peoples. Uzbekistan has been steadily cooperating with the UN within the framework of issues such as maintaining peace and stability, solving environmental problems, and socio-economic development. Establishing a particularly active political dialogue has become one of the main directions of Uzbekistan's cooperation with the UN.