The objective of this report is to find out the accuracy of Ultrasound (US) in diagnosing the appendicitis. We conducted systematic review of databases Medline, Embase and Cochrane to find out the answer to research question. The articles were selected based on inclusion and exclusion criteria, and finally 17 studies were collected. Sensitivity and Specificity for diagnostic accuracy of US was 69% and 81% respectively. It does not involve radiations. Most US examinations are indeterminate for diagnosing appendicitis. And for evaluating the appendicitis CT is considered as preferred line of imaging test. The patients having appendicitis may not get benefitted from US diagnosis alone and may be recommended for more specific methods of diagnosis.