The present document is the first written presentation of the Virtual Human Twin (VHT) vision as it has been prepared by the EDITH consortium and discussed with representatives of the wider ecosystem. After a brief statement on the genesis of the vision, the document is composed of two main parts: the outline of the VHT roadmap and the elaboration of the vision for the integrated Virtual Human Twin. It ends with an overview of the coming activities that will lead to the completion of the full draft of the VHT roadmap. If you would like to give feedback on this text, you can do so via the project website: https://www.edith-csa.eu/materials/. if you would like to stay updated on EDITH's progress, you can enter your details via the contact form on the website: https://www.edith-csa.eu/contact/

EDITH is a Coordination and Support Action funded by the European Commission under the Digital Europe Programme under grant agreement n. 101083771.