Oral disintegration tablets are the novel technology for administration of the drug through the oral route. The tablet is the most widely used dosage form because of its convenience in terms of self -administration, compactness and ease in manufacturing. Oral Disintegrating tablets have been found to be the choice for Psychiatric as well as patient suffering from stroke, thyroid disorder, Parkinson’s diseases and multiple sclerosis, patients with nausea, vomiting and motion sickness. ODTs may Show increased oral bioavailability, good stability, accurate dosing, easy manufacturing, small packaging size, and easy to handle by patients.This research paper is about to formulation & evaluation of almotriptan oral disintegrating tablets. Keywords:Disintegration,compactness, bioavailability, stability.