Bilayer (and multilayer) tablet-based therapeutic strategies are becoming more popular among both brand-name and generic medications as a result of a number of interrelated aspects, such as sophisticated delivery methods, patient compliance, and combination therapy. In order to successfully manufacture these increasingly sophisticated systems, a number of obstacles must be overcome, ranging from formulation design through tablet press monitoring and control. The key advantages of this class of oral dosage forms are highlighted in this article, which also gives a summary of the most recent developments in bilayer tablet technology. It also describes the present obstacles to improving production procedures and product quality. Keywords: Bilayer tablet technology, generic medication, oral dosage forms