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The kind of novel herbal formulations such as polymeric nanoparticles, nano capsules, liposomes, phytosomes, animations, microsphere, transferosomes and ethosomes has been reported using proactive and plant selections. The novel formulations are described to have remarkable over conventional formulations of plant actives and extracts which includes enhancement of solubility, bioavailability, and protection from toxicity, enhancement of pharmacological activity, enhancement of stability, improved tissues microphages distribution, sustained delivery, and protection from physical and chemical degradation . Phytosomes are cell – like small structure and advanced from herbal formulation and it is made up of active phytoconstituents of herbal extract surrounded by lipid bilayer, consisting of phosphatidylcholine. and it include high lipophilicity, enhanced bioavailability, and high stability. Liposomes are spherical vesicles made up of phospholipid bilayer used as colloidal vesicular drug delivery systems .and in this review we also summarized about nano particles, emulsions, microspheres, ethosomes, solid lipid nano practical, niosomes, proniosomes , dendrimers , liquid crystals, hydrogels. Keywords: Herbal Formulation, Novel Formulation, Liposomes, phytomes, Nano particles
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