Background: Low back pain is a very common health problem amongst population and a major cause of disability that affects work performances and well-being. It is can be acute, sub-acute or chronic. It is affects all ages of the population and is the most common reason for medical consultations. The main aims of study: To assessment the level of nurses` knowledge of lower back pain exercises, to identify the difference between nurse`s knowledge level in lower back pain exercise according to demography variables and knowing the percentage of nurses who pass and not pass regarding lower back pain and it`s exercises. Methodology: This study included a sample of (60) nurses, (26) males and (34) females, this study was conducted on the nursing staff in various hospitals. The questionnaire was used to collect the required information and it is composed of (24) questions about lower back pain and it`s exercises in different cases, regarding the score (I strong agree=2, I agree=1, I don't agree=0) where total scores=48 and also include variables (level of education, and years of experiences). And use the statistical program (spss) to analyze the results. The data were analyzed using the Statistical Package for Social Sciences (SPSS), version 26. Conclusions · More than half of the sample they got (16 to 31) score was having medium level of knowledge. · Sample study got (83 %) pass regarding information of lower back pain domain and sample study got (72 %) pass regarding exercise domain of lower back pain. Recommendations · Add physiotherapy in the curricula of health institutes and colleges of nursing. Give training courses for nurses who working at hospital in another unites about how deal with lower back pain and it`s exercises