Cosmeceuticals means combination of cosmetics and pharmaceuticals. Cosmeceuticals are cosmetics products with biologically active ingredients purporting to have medical or drug-like benefits. Cosmeceuticals are used to improve and nourish the skin appearance and known to treat different dermatologic conditions, like cosmetics, cosmeceuticals are also applied topically having ingredients that influence the skin’s biological function. Cosmeceuticals are meant to improve appearance by delivering nutrients necessary for healthy skin. cosmeceuticals usually claim to reduce wrinkles and to improve tone, texture and radiance of the skin. Cosmeceuticals products of herbal origin are most liked among clients as they are mostly non toxic and holding strong antioxidant activity. Cosmeceuticals products can be a drug, a cosmetics, or a combination of both. But the term ‘cosmeceuticals’ has no meaning under the law. Cosmeceuticals are not subject to be review by the Food and Drug Administration. (FDA) and the term cosmeceuticals is not recognized by the federal food drug and cosmetics act. Although cosmetics and cosmetics and cosmeceuticals both are being tested for their safety and tested to determine weather beneficial ingredients actually live up to a manufacture's claim is not compulsory. The “cosmeceuticals” label applies only to products applied topically, such as creams, lotions and ointments, cosmetic labels do not have any divisions between active ingredients that are essential, they are all listed together. Sadick NS. Their role in dermatology practice. Cosmeceuticals represent a new category of products placed between cosmetics and pharmaceuticals that are intended for the enhancement of both the health and beauty of skin. Encompassing an ever-increasing part of the skin care industry, cosmeceuticals are formulated from a multitude of ingredients Keywords : Cosmeceuticals, cosmeceutical chemistry, regulatory aspects, skin cosmeceutical, sunscreen agents, moisturizing agent, antiaging.