In this report, we summarize the NEANIAS project key results achieved over the course of its 36 month duration. During its lifespan, despite the continuous international pandemic crisis, NEANIAS managed to successfully achieve its objectives; managed to release effectively both the expected as well as additional software and open science cloud solutions; managed to broadly disseminate, communicate, as well as shape effectively the overall exploitation of the thematic, core and further business cases; managed to establish fruitful collaborations, innovation activities, undertake a leading role in EOSC exploitation and user-engagement, thus, strengthening and securing the overall project’s impact.