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This contains the supplemental material of the following article: NaCl 3% bolus therapy as emergency treatment for severe hyponatremia: Comparison of 100 ml versus 250 ml., Karen Massop, MD, Dieneke A Haverkort, MD, Anneke P Bech, MD, PhD, Hans de Boer, MD, PhD, The Journal of Clinical Endocrinology & Metabolism, 2023;
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