integration_instructionsResearch softwarekeyboard_double_arrow_right Software 15 Nov 2022Publisher:ZenodoFunded by:NIH | Multiscale theory of syna..., UKRI | Manufacture of renewable ..., NIH | Modeling and analysis of ...

Authors: Bonilla-Quintana, Mayte; Rangamani, Padmini;

doi: 10.5281/zenodo.7686060 , 10.5281/zenodo.7686061 , 10.5281/zenodo.10114856

Biophysical 3D modeling of actin-mediated structural plasticity

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Abstract

Simulation of dendritic spine enlargement upon LTP stimulation using PDEs for actin, arp2/3, and cofilin dynamics in a moving boundary framework. Run Simulation_main.m For the remeshing function (remeshing.m) see https://github.com/christopherhelf/isotropicremeshing/blob/master/README.md and the instructions therein.

This work was supported by the NIH Grant Number 1RF1DA055668-01 and by an Air Force Office of Scientific Research Grant FA9550-18-1-0051 to P.R.

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University of California, San Diego
United States

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Biophysical Modeling of Actin-Mediated Structural Plasticity Reveals Mechanical Adaptation in Dendritic Spines
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