Deliverable 11.1 for the WorldFAIR Project’s Ocean Science Work Package (WP11). This report provides a synoptic overview of how cross-domain interoperability may be built from within WorldFAIR’s Oceanography case study (Work Package 11). After an introduction to the Intergovernmental Oceanographic Commission of UNESCO’s Ocean Data and Information System (ODIS), the report summarises an evaluation of FAIR Implementation Profiles and FAIR Enabling Resources compiled in WorldFAIR’s WP2. It then summarises and synthesises supplementary insights obtained through a survey distributed across WorldFAIR partners, and identifies a pathway to implement sustainable cross-domain (meta)data flows to inform and support the development of the Cross-domain Interoperability Framework (CDIF). The WorldFAIR case studies on biodiversity, disaster risk reduction, chemistry, and cultural heritage were identified as focal points to bridge with ODIS, being complementary to the strategic priorities of marine science and sustainable ocean management and offering clear socio-technical interfaces compatible with ODIS’s own interoperability approaches. The high-level roadmap in Section 4 of this report outlines the general approach that will be pursued in the remaining tasks in WP11, namely the expansion of ODIS interoperability conventions to interface with those prevailing in the target use cases alongside the implementation and testing of (meta)data exchanges with independent stakeholders from the target domains. Visit WorldFAIR online at http://worldfair-project.eu. WorldFAIR is funded by the EC HORIZON-WIDERA-2021-ERA-01-41 Coordination and Support Action under Grant Agreement No. 101058393.