Literature search till the beginning of 2022 for all relevant studies publish in English language among different databases such as; PubMed and Embase. Many physical, emotional, and social symptoms may be present in COPD patients, necessitating a comprehensive, targeted intervention in the form of a personalized pulmonary rehabilitation (PR) program. Taking into account the disease's complexity and severity, good PR must incorporate the translation of information and evidence of recognized aspects into a multidimensional, complex intervention. In this manner, PR will increase the patient's individual autonomy and maximize the patient's autonomy and community functioning. PR is defined as a comprehensive strategy designed to sustainably enhance physical, psychological, and social outcomes in individuals with chronic respiratory problems. PR is a personalized, sophisticated health care intervention. Although exercise training has been recognized as the cornerstone of a comprehensive PR program, a profound pathophysiology understanding of the mechanisms governing exercise tolerance, particularly in COPD patients, necessitates the consideration of several training modalities.