Introduction: Stroke is significant global health problem and major cause of mortality and morbidity in developed countries and increasingly in low-middle income countries. In 2016, Global Burden of Disease project estimated the number of incident cases of stroke in India to be 1,175,778 and number of deaths due to stroke to be 9.4 million. Metabolic syndrome is known as an independent risk factor of stroke. Objectives: 1. To estimate prevalence of metabolic syndrome among Ischemic stroke patients. 2. To assess the association between metabolic syndrome and Ischemic stroke 3. To assess the association between Diabetes Mellitus type 2 and Ischemic stroke Methods: A observational study was performed on 100 out patients and inpatients admitted in Basaveshwara Teaching and General Hospital attached to Mahadevappa Rampure Medical College Kalaburagi for a period of 1 year. A detailed history was collected from qualifying patients using a pre-designed, structured proforma. Further, general examination and a detailed systemic examination, followed by relevant investigations (FBS: A blood sample is taken after an 8 hour overnight fast., Fasting Lipid Profile) were conducted and the results were noted. Results: Prevalence of metabolic syndrome in this study was 58 (58%) of them presented with metabolic syndrome. Higher prevalence was observed in 50-59 years age group 17 (74%) and among males 43 (64.3%). Smoking and diet were significantly associated with metabolic syndrome. Mean values of the components of metabolic syndrome were significantly higher in patients with metabolic syndrome. Prevalence of Diabetes was 73% and among them majority presented with metabolic syndrome. Diabetes Mellitus was significantly associated with stroke. Conclusion: In this study both metabolic syndrome and Diabetes Mellitus were significantly associated with stroke. Hence, they can be used as independent predictors for stroke.