The goal of this article is to present the most recent information about the "tomato flu" outbreak in India. A new disease recently sprung out in some regions of India. The illness had a rash that was primarily seen in children under the age of nine and was extremely contagious. It was called "tomato flu" because the rash was excruciatingly painful and the blisters were the size of tiny tomatoes. Tomato flu is considered a “Hand, Foot and Mouth disease”. The two main viruses causing HFMD are human enterovirus 71 (EV-A71) and coxsackievirus A16 (CV-A16). In most situations, the clinical presentation is minimal. The infection is self-limiting and will go away on its own in 7–10 days. The therapy is generally composed of symptomatic, supportive care, isolation, and maintaining hygiene norms.