Background- There is discussion over the biomarker potential of using different lipid fractions to predict the risk of acute myocardial infarction (AMI). In order to compare the lipid profiles of 67 AMI patients, we looked at serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglycerides (TG). Material And Method- A prospective, cross-sectional study was conducted in the SAIMS emergency/opd. Within 24hours of onset of chest pain. All patients admitted with AMI were included after providing informed consent. Results- Among 200 AMI Patients included 100 STEMI (ST- elevated myocardial infarction) patients, 100 NSTEMI (non-ST-elevated myocardial infarction) patients. The median age of STEMI patient was 57.7years while that of NSTEMI patients 60.3 years. BMI of STEMI 24.6 kg/m2 and NSTEMI 24.9 kg/m2. History of diabetes was present in 22% STEMI patient while that of NSTEMI patients 39%. History of hypertension is present in 52 % STEMI patient and 68% of NSTEMI patients. 49 % STEMI patients were currently smoking while only 36% among NSTEMI patients. Conclusion- The lipid paradox exists for STEMI patients LDL-C and TC levels and hospitalisation, 30-day, and 1-year mortality. NSTEMI patients have a lipid pseudo-paradox. HDL-C, myocardial infarction type, and hospital death are interrelated. These results need more study.