Media has a substantial impact on public perception of events, and, accordingly, the way media presents events can potentially alter the beliefs and views of the public. One of the ways in which bias in news articles can be introduced is by altering word choice. Such a form of bias is very challenging to identify automatically due to the high context-dependence and the lack of a large-scale gold-standard data set. In this paper, we present a prototypical yet robust and diverse data set for media bias research. It consists of 1,700 statements representing various media bias instances and contains labels for media bias identification on the word and sentence level. In contrast to existing research, our data incorporate background information on the participants’ demographics, political ideology, and their opinion about media in general. Based on our data, we also present a way to detect bias-inducing words in news articles automatically. Our approach is feature-oriented, which provides a strong descriptive and explanatory power compared to deep learning techniques. We identify and engineer various linguistic, lexical, and syntactic features that can potentially be media bias indicators. Our resource collection is the most complete within the media bias research area to the best of our knowledge. We evaluate all of our features in various combinations and retrieve their possible importance both for future research and for the task in general. We also evaluate various possible Machine Learning approaches with all of our features. XGBoost, a decision tree implementation, yields the best results. Our approach achieves an -score of 0.43, a precision of 0.29, a recall of 0.77, and a ROC AUC of 0.79, which outperforms current media bias detection methods based on features. We propose future improvements, discuss the perspectives of the feature-based approach and a combination of neural networks and deep learning with our current system.