Significant quantities of infectious waste, including microbiological debris, contaminated sharps, and pathologic wastes such as blood specimens and blood products, are generated by clinical laboratories. The majority of laboratory trash can be disposed of with normal solid waste. A literature search performed through electronic databases, for all relevant studies that were published in English language up to 2022. The present examination of laboratory waste management methods reveals that segregation was the most challenging step. This may be the result of insufficient or inconsistent laboratory manager and employee training. Due to the lack of comprehensive and generally agreed definitions of infectious waste types, certain types of domestic trash, such as soiled but not blood-saturated cotton or stool samples, are deemed contagious.