Introduction: The main objective of this study was to assess the quality of life of women with breast cancer in Kinshasa in order to identify the repercussions of this pathology on the mental life of these women. In addition, the study aims to determine the effect of socio-demographic variables on the quality of life of these women. Methods: The study sample consisted of 61 women with breast cancer treated at the University Clinics of Kinshasa. The McGill Quality of Life Rating Scale was administered to the study subjects. The survey took place throughout the month of July 2021. Results:women with breast cancer show a state of general and physical ill-being. They experience a strong sense of psychological, emotional and social well-being. The number of children variable influenced the psychological well-being of these women. The cancer stage variable influenced the psychological well-being of these women. Conclusions: the breast cancer suffered by these women negatively affects their general and physical well-being. The psychological, emotional and social well-being of these women is not affected, and this, because of the integral care at the University Clinics of Kinshasa which contributes to the restoration of the affects of the latter.