In the entire world COVID-19 disease has been spread rapidly in December 2019 and now it has been almost 2 years we are facing the trouble of COVID-19 disease condition. Till now we have very less evidence based options for the treatment and prevention. In the COVID -19 Pandemic public health being focused towards the healthy living, hygiene and nutritional dietary routine. COVID-19 patients are at the high risk of nutritional imbalance and thus weak immunity. Due to lack of the specific treatment preventive measures have been focused majorly and here nutrition plays the important role. Since ancient times, nutritional diet, micronutrients and vitamins have been proved best to boost the immunity against viral infections. Deficiency of micronutrients and fat soluble vitamins leads to the weak immunity. Several statistical data and evidences shows that people with weak immunity are being targeted by COVID-19 Virus.Various cross-sectional study, data analysis and clinical trials have been performed to investigate the role of micronutrients in COVID-19 diseased condition. Several recent reports have found the greater risk for the COVID-19 patients associated with other severe diseases like respiratory tract infection, kidney related problems, diabetes, hypertension Etc. Detailed Clinical Trials will be focused more in the future.The various available scientific data, evidences, statistical analysis, reviews, surveys and clinical trials are studied and the collection of these information together forms this effective article. I ensure that, due to the research based evidences presented in this article, this article is being the worthy in all.