Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Article . 2023
License: CC BY
Data sources: ZENODO
addClaim

Polygenic gene editing: the next frontier in genomic medicine?

Authors: Visscher, Peter; Gyngell, Christopher; Yengo, Loic; Savulescu, Julian;

Polygenic gene editing: the next frontier in genomic medicine?

Abstract

Data and R scripts to generate Figures - Perspective paper on Gene Editing - Visscher et al. (2023) This folder contains GWAS summary statistics (genome-wide significant SNPs only) for various traits and diseases, as well as R scripts to generate Figures from our Perspective paper on Gene Editing. Data Files FG_36snps.txt: Fasting Glucose - data from Lagou et al. (2021) WHRadjBMI_Pullit_et_al2018.txt: Waist-Hip Ratio adjusted for BMI - data from Pullit et al. (2018) GLGC_Graham2021.txt: Summary statistics for LDL, (log) Triglycerides - data from Graham et al. (2021) ICBP_Warren2022.txt: Summary statistics for blood pressure phenotypes (systolic and diastolic) - data from Warren et al. (2022) ad_marioni2018_ukbf.txt: Summary statistics for Alzheimer's Disease - data from Marioni et al. (2018) mdd_howard2019_ukbf.txt: Summary statistics for Major Depression Disorder - data from Howard et al. (2019) scz_ng2014_ukbf.txt: Summary statistics for Schizophrenia - PGC consortium (2014) t2d_Vujkovic2020.txt: Summary statistics for type 2 diabetes - ref. https://www.nature.com/articles/s41588-020-0637-y#Sec45 cad_aragam2021.txt: Summary statistics for Coronary Artery Disease - ref. https://www.medrxiv.org/content/10.1101/2021.05.24.21257377v1.full.pdf summary_stats_GWS_Yengo_Savage_2018_v2.Rdata: Summary statistics for height and BMI (Yengo et al. (2018)) and IQ (Savage et al. (2019)). R Script Files Figure_1.R Figure_2.R

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
    OpenAIRE UsageCounts
    Usage byUsageCounts
    visibility views 3
    download downloads 15
  • 3
    views
    15
    downloads
    Powered byOpenAIRE UsageCounts
Powered by OpenAIRE graph
Found an issue? Give us feedback
visibility
download
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
OpenAIRE UsageCountsDownloads provided by UsageCounts
0
Average
Average
Average
3
15
Green