Introduction: This study evaluates relationship between serum lipid profile and preeclampsia1 . Objective:The study is to compare the mean lipid levels in pre-eclamptic and normal pregnancy. Design:This is a descriptive study. Participants: Among patients attending Out Patient Department in Chalmeda Anand Rao institute of medical sciences, 25 singleton pregnancies diagnosed as having preeclampsia and 25 pregnancies without such diagnosis were included in study. Outcome measures: Risk of preeclampsia, pregnancy induced hypertension, preterm birth, small/large for gestational age and child loss. Results:In pre-eclamptic mean triglycerides levels were (254 mg/dl ± 0.45 versus 116.59 ± 4.9) significantly higher than normal controls (p<0.05). Mean HDL-Cholesterol levels were (36.92 mg/dl ± 7.70 versus 51 ± 5.46) statistically significantly higher than normal controls (p<0.05). Mean LDL-Cholesterollevels were(132.95mg/dl ± 32.26 versus 99.36 ± 17.75) statistically significantly higher in pre-eclamptic as compared to normal controls (p<0.05). Conclusion: Pre-eclamptic women had deranged lipid profile as compared to normal pregnant women.