The increasing population in the world and the need for construction and cement use are increasing day by day. Products that can be used instead of cement are being researched in order to prevent the damage to nature and the energy spent during the cement production stages. Materials that can be used instead of cement are called pozzolans, they are fine-grained structures that exist in nature or are activated later. Most of the pozzolans that are not obtained naturally are in the form of slag. Mine wastes formed after metallurgical processes are called smelting slag. These products, which are obtained as a result of thermal and recovery processes, are waste, but they are a secondary raw material source that can be brought into the economy by secondary processes. The major sources frequently used as pozzolans today are blast furnace slag and steel slag. In this study, it was aimed to determine the pozzolanic activity of heat-treated waste from old mine slags. Samples obtained from the mine waste site were ground to cement size. In order to examine the pozzolanic properties and grindability of the mine waste in the Amasya region, it was reduced to different sizes by grinding at different cycles and times (20, 30, 40, 60, 90 and 120 minutes). The obtained products were analyzed by sieve analysis and the relationship between chemical content, time and cycle was revealed. It is important in which time and cycle the particle size will decrease and the pozzolanic activity will increase. Then, in order to determine the pozzolanic activities, mixtures with pozzolan substitutes were prepared for cement in different ratios, and strength activity indexes were determined at the end of 7/28 day curing periods. As a result of the study, 700 dv./min. in the grinding process, the number of balls does not affect the grinding process, 1000 dv./min. It was observed that the grinding speed significantly reduced the slag and the specific surface area values increased significantly.