The failure to give adequate postoperative analgesia has multiple causes. Insufficient understanding, concern about analgesic medication-related concerns, inadequate pain evaluation, and limited personnel are among the factors. This review will focus on the management of acute postoperative pain as well as the history and classifications of debridement. We did a comprehensive literature search of relevant research on the therapy of acute postoperative pain and will explain the background and types of debridement using the PubMed (Midline) database up to 2022. Debridement is considered an essential component of wound-bed preparation, as it removes impediments to wound healing. However, there is currently insufficient evidence to favor one debridement procedure over another; hence, the choice of which method to employ is dependent on the clinician's skill and judgment. As inadequate care can result in delayed recovery, increased discomfort, an increased risk of infection, and the inappropriate use of wound dressings, all of which have a negative influence on a patient's quality of life, experts must be well conversant with all debridement options. Patients with chronic injuries face a number of concerns, including pain, movement restrictions, social isolation, and mental issues. As the ultimate goal of wound management is to improve a patient's complete quality of life, care planning must incorporate all of these factors while simultaneously preparing the injury bed for recovery. It is essential to recall that certain debridement techniques necessitate the practitioner's ability to attend to minute details.