Objective: A growing number of research on fibroid disease among women and methods of treatment. The goal of this systematic review was to spot light on fibroid disease prognosis and to determine the methods of treatment used in Kingdom of Saudi Arabia (KSA). Methods: Authors began with recognizing the important examination proof that spots light on fibroid disease prognosis and to determine the methods of treatment used in KSA. We led electronic writing look in the accompanying data sets: Ovid Medline (2010-present), Ovid Medline Daily Update, Ovid Medline in process and other non-filed references, Ovid Embase (2010-present), The Cochrane Library (latest issue) and Web of Science. Just examinations in English language were incorporated. The precise selection was acted in close collaboration with a clinical examination curator. Results: A total of 19 studies were identified in the search, all of them were assessed for eligibility, and 6 articles were included in this review.HIFU is now utilized therapeutically in the treatment of leiomyomas in gynecologic oncology. Since the 1990s, when clinical studies of HIFU treatment for leiomyomas first started, HIFUNIT 9000 and prototype single focus ultrasound devices have been used to treat the vast majority of leiomyoma patients. Excellent-intensity focused ultrasound (HIFU) is a non-invasive, gold-standard therapy for all sizes of leiomyomas, with high effectiveness, minimal surgical morbidity, and no systemic adverse effects. Conclusion: Fibroids of the uterus that were causing symptoms responded well to HIFU therapy. The literature on embolization of the uterine artery is sparse (UAE). HIFU is a great choiceto treat fibroids in your uterus.