This paper, through the concept of experience, aims to elucidate the criticisms that A. N. Whitehead brought to the modernity and scientific universe designs of the seventeenth-eighteenth centuries. According to Whitehead, distinction of substance- quality and its transformations of modern – cartesian, interrupts all the relations of ‘being’ with ‘being’. Furthermore, by the end of the seventeenth century, while the developments in physics, caused a disregard for the importance of philosophy, it confirmed the distinction of the mind with the outside world. The design of reality based on abstractions of the period leads to the perception of these abstractions that appear as a product of reason as concreteness, while the rest is pushed into the realm of insignificance. Thus, the nature turns into a lifeless, colorless and aimless contrariety. However, the concept of ‘experience’, as considered with its essence, is not the mere experience of something, but realizing the entire world as an experience. In such an activity, every drop of experience interconnects with the all other drops of experience. For Philosophy of Organism, this experiential whole, points out the fundamental for the constitution of the universe.