ABSTRACT OTC medicines are medicines sold directly to a consumer without a prescription from a healthcare professional. Which are legally allowed to be sold by pharmacists which is also known as non-prescription medicine. OTC medicines have Advantages and Disadvantages Healthy adults who utilize OTC prescriptions periodically and appropriately have an okay of unfavorable effects. However, certain individuals are at more serious risk, utilization of OTC drug might cause unsafe effects. In this condition we should know about OTC medication. Here examined about OTC meds in specific unhealthy circumstances and their viewpoints, for example, Asthma, Diabetes, Hypertension, Hyperlipidaemia, and Hear failure. Use of non prescription drugs in this situation may leads to harmful effects there for every patient and pharmacist should be aware about it. Patient counselling plays important role in effective treatment. The safe and effective use of drugs depends on patients’ information about their medication .During counselling the pharmacist should assess the patient’s understanding about their illness and treatment and supply individualized advice and data which can assist the patients to require their medication. Patient counselling is an essential component of clinical pharmacy practice in hospital and in community pharmacy settings. Counseling enhances the patients understanding of their illness and its treatment and may improve adherence and therapeutic out come. It allows pharmacists to gain first hand knowledge of medication use from the patients perspectives. Keywords: OTC medicines, Patient counseling,non prescription