Antarctic Ice Sheet simulations driven by CMIP6 climate models under historical and SSP5-8.5 scenarios This dataset contains output ice sheet model runs forced by climate boundary conditions provided by CMIP6 climate model output. Each experiment set is archived in separate compressed tar.gz files. Description of the experiment sets, including the model setup, key parameters, climate forcings, and their main objectives are documented in Table 1 of Li, DeConto, Pollard (2023) Climate model differences contribute deep uncertainty in future Antarctic ice loss, Science Advances. Two kinds of output are included in each ice sheet run: fort.22 files contain time series of several key variables for the Antarctic Ice Sheet (area, volume, sea-level equivalent, etc.); fort.92.nc files contain 2D and 3D fields such as ice thickness and velocity at specific time slices.