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Modeling the Sequence Dependence of Differential Antibody Binding in the Immune Response to Infectious Disease

Name: Modeling the Sequence Dependence of Differential Antibody Binding in the Immune Response to Infectious Disease
Keywords: 3. Good health

Research datakeyboard_double_arrow_right Dataset 29 Nov 2022Publisher:Zenodo

Authors: Chowdhury, Robayet; Taguchi, Alexander; Kelbauskas, Laimonas; Stafford, Philip; Diehnelt, Chris; Zhao, Zhan-Gong; Williamson, Phillip; +2 Authors

doi: 10.5281/zenodo.7377843 , 10.5281/zenodo.7752734 , 10.5281/zenodo.7377844

Modeling the Sequence Dependence of Differential Antibody Binding in the Immune Response to Infectious Disease

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Abstract

Raw peptide microarray data of fluorescence intensities representing relative binding of antibodies in sera samples collected from different cohorts of patients diagnosed with a number of viral infections. Healthy controls are also included. Columns: Sequence - peptide sequence HCV - Hepatitis Virus C Dengue - Dengue virus WNV - West Nile Virus HBV - Hepatitis Virus B Chagas - Chagas disease ND - negative/healthy donor LowCV - low coefficient of variation HighCV - high coefficient of variation

The data that was used in this analysis was collected under Chemical Biological Technologies Directorate contracts HDTRA-11-1-0010, HDTRA1-12-C-0058 from the Department of Defense (Defense Threat Reduction Agency, DTRA).

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Arizona State University
United States

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