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Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Oct 2021Embargo end date: 13 Oct 2021 Switzerland English Publisher:American Chemical Society (ACS)Journal:Journal of the American Chemical Society, volume 143, pages 16,313-16,319 (issn: 0002-7863, eissn: 1520-5126, Copyright policy )Funded by:EC | CRISPR2.0, EC | chromo-SUMMIT, SNSF | Molecular mechanisms of C... +1 projects
Authors: Makasheva, Kristina; Bryan, Louise C.; Anders, Carolin; Panikulam, Sherin; Jinek, Martin; Fierz, Beat;

doi: 10.1021/jacs.1c06195 , 10.5281/zenodo.7360318 , 10.5281/zenodo.7360319 , 10.5281/zenodo.7390421 , 10.5281/zenodo.7390420 , 10.5167/uzh-210326

pmid: 34597515

pmc: PMC8517959

Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor

Abstract

Raw single-molecule data for Figures 3 and 4 of the indicated manuscript. Details are found in the included txt files.

Country
Switzerland
Related Organizations
Keywords

Gene Editing, 1303 Biochemistry, 1503 Catalysis, 610 Medicine & health, 1600 General Chemistry, 1505 Colloid and Surface Chemistry, DNA, Single Molecule Imaging, Nucleosomes, CRISPR-Associated Protein 9, 10019 Department of Biochemistry, 570 Life sciences; biology

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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