ABSTRACT Vanadium toxicity to fish Heteropneustes fossilis (Bloch) was studied for a period of two weeks. Haematological parameter like Total Erythrocyte Count (TEC), Haemoglobin (Hb) and Total Leucocyte Count (TLC) altered significantly ( P < 0.001 ) in fish when exposed to 1,4, and 7 ppm of Vanadium (NaVO3). Absolute value like MCH changed in accordance with the above parameter. Key Words: Seasonal changes, Chiloscyphus gollani, Solenostoma crenulata, Fossombroni himalayensis, inverse relation. REFERENCES Bannerjee V and Banerjee M .1988effect of heavy metal poisioning on peripheral haemogram in Heteropneustes fossilis (Bloch) mercury,chromium and zinc chloride (Lc50),comp. physiol ,ecol,13(2), 128-134 Porika Raju and Estari Mamidala (2015). Anti-diabetic activity of compound isolated from Physalis angulata fruit extracts in alloxan induced diabetic rats. The Ame J Sci & Med Res, 2015,1(1); Pages 1 -6. doi:10.17812/ajsmr2015.11.1 Cheng I.W., M. A Albayati., M .R. Culbertson , L S Rosblatt & L.D. Hansen 1982.Acute toxicity of Ammonium metavanadate in mice, J.Toxicol & Environ Health,10 : 673-687. Dacie J.V and S.M.Lewis 1975. Practical haematology , J & A Churchill ltd, London, UK Gummow B. 2011. Vanadium: Environmental Pollution & Health effects. Elsevier B.V, 628-636. Gupta S. & V Rai.1995.Effect of Vanadium on phosphatases and transaminases in certain organs of Clarias batrachus , 22,71-77 Nanda, P. and M.K. Behera 1996 .Nickel induced changes in some haematobiochemical parameters of a cat fish Heteropneustes fossilis (Bloch). Env.Ecol. 14 :82-85.