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Article . 2022
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Article . 2022
License: CC BY
Data sources: Datacite
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DESIGN AND IN-VITRO EVALUATION OF SUBLINGUAL TABLETS OF ZOLPIDEM TARTRATE

descriptionPublicationkeyboard_double_arrow_right Article 22 Nov 2022Publisher:Zenodo
Authors: Botla Manohar, Pranay Renukuntla, Daniel Kothapally;

doi: 10.5281/zenodo.7348496 , 10.5281/zenodo.7348497

DESIGN AND IN-VITRO EVALUATION OF SUBLINGUAL TABLETS OF ZOLPIDEM TARTRATE

Abstract

The sublingual tablets of zolpidem were prepared by direct compression method using Ludiflash, Prosolv HD 90, and F-melt with varying concentrations. The developed sublingual tablets were evaluated for pre-compression and post-compression parameters. The results of all formulations were found within the pharmacopeia limits. The optimized formulation (F9) with F-melt (25%) showed the maximum percentage of drug release was 98.79% in 30 min and used for short-term treatment of insomnia. The disintegration time, drug content, wetting time, and water absorption studies were evaluated for all the formulations. Keywords: Zolpidem, sublingual tablets, direct compression, and water absorption ratio

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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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