Femur is the most fractured long bone in the body that often necessitates surgical fixation. One of the most challenging complications in trauma surgery is infection after fracture fixation (IAFF). Herein we presented A 39 years old male drug addict , he underwent close reduction and internal fixation right femur fracture on 2013 with no follow up in primary hospital. On July 2017 he presented to our hospital with a history of pain in his right thigh, the clinical examination showed a sinus discharge from right thigh, he was controlled by irrigation and debridement and inserting of antibiotics tens nail. He was followed up by X-ray scanning. On August 2018 patient presented with broken plate and fibula graft, after removal of broken plate and application of double plate for right femur fracture the X-ray scan show callus formation. Keywords: Surgical treatment, Orthopedic, Implant, Infection, Femur, Fracture.