The utilization of a face mask is a necessity during the SARS CoV2 pandemic. The occlusion associated with prolonged daily use can lead to physiological changes in the skin, resulting in irritation, itching and infection. This may lead to exacerbation of pre-existing dermatoses or induction of irritant dermatitis or bacterial folliculitis.We are reporting in this study a case series, aiming to explore the prevalence and possible risk factors for preventing face mask-related acne.