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RNA sequencing of A2780 cells treated with CCL2 identified genes associated with A2780 cell growth

descriptionPublicationkeyboard_double_arrow_right Article 02 Aug 2022Publisher:Zenodo
Authors: zhenling ma;

doi: 10.5281/zenodo.7326003 , 10.5281/zenodo.6951667 , 10.5281/zenodo.6951668

RNA sequencing of A2780 cells treated with CCL2 identified genes associated with A2780 cell growth

Abstract

Exogenous CCL2 promotes A2780 cell activity. RNA sequencing was used to identify the transcriptomic changes in CCL2-treated A2780 cells. Based on |log2 Fold Change| > 1 and and p < 0.05, 190 differentially expressed genes were selected. Of these genes, 82 were observed to be upregulated and 108 downregulated.The gene ontology analysis of differentially-expressed genes was performed to identify the underlying functions and biological processes. In addition, the expression of the topmost upregulated genes was verified by qPCR.

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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