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Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids

descriptionPublicationkeyboard_double_arrow_right Article 23 Nov 2022Embargo end date: 28 Oct 2024 United States English Publisher:American Society for MicrobiologyJournal:Journal of Virology, volume 96 (issn: 0022-538X, eissn: 1098-5514, Copyright policy )Funded by:EC | OrganoVIR, EC | CM_GF, NIH | GASTROINTESTINAL HORMONE ...
Authors: Carmen Mirabelli; Nanci Santos-Ferreira; Merritt G. Gillilland; Roberto J. Cieza; Justin A. Colacino; Jonathan Z. Sexton; Johan Neyts; +3 Authors

doi: 10.1128/jvi.00855-22 , 10.5281/zenodo.7307413 , 10.5281/zenodo.7307412 , 10.7302/24553

pmid: 36342297

pmc: PMC9683019

handle: 2027.42/195358

Human Norovirus Efficiently Replicates in Differentiated 3D-Human Intestinal Enteroids

Abstract

The human norovirus (HNoV) clinical and socio-economic impact calls for immediate action in the development of anti-infectives. Physiologically relevant in vitro models are hence needed to study HNoV biology, tropism, and mechanisms of viral-associated disease, and also as a platform to identify antiviral agents.

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Keywords

570, Pyrimidines, Norovirus, Nitriles, Humans, Pyrazoles, Antiviral Agents, Caliciviridae Infections, Gastroenteritis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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OpenAIRE UsageCountsViews provided by UsageCounts
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